Contract · Federal · No Set aside used

Whole genome sequencing for investigation of age-related chronic disease in HANDLS participants

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
Location: Brooklyn, MD
Amount: Amount not listed
Posted: Sep 14, 2026
Set-aside: No Set aside used
NAICS code: 541714 - Scientific Research and Development Services (general category) look up NAICS codes
PSC code: Q301 - Medical Services (general category)

Timeline

Posted

Sep 14, 2026
Status

Closing soon

What contracts like this typically pay

No award history yet for this category (NAICS 541714).

What this contract is for

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
Location: Brooklyn, MD
Set-aside: No Set aside used
NAICS: 541714 - Scientific Research and Development Services (general category)
Scope: Federal

Investigators in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study require whole genome sequencing (WGS) processing to expand our current research examining whether genetic variants contribute to age-related chronic diseases.

Samples from HANDLS participants have been collected over 20 years and many are over 10 years old.

A contract is required because the Government does not have available facilities or resources to perform this work consistent with other WGS performed on other HANDLS samples.

The objective of this work is expanding our current research to examine health differences associated with age-related chronic diseases through whole genome sequencing to investigate the contributions of genomics to the burden of disease incidence, prevalence, morbidity, and mortality in populations within the United States.

The long-term goal is to create a consistent dataset of whole genome sequencing to complement the longitudinal HANDLS behavior and health data.

The contractor will deliver plates to the Government sufficient to run 600 samples, some of which have been stored for ten or more years.

The contractor will perform whole genome sequencing, and specifically shall: Sequence libraries on the NovaSeq X-Plus platform with 25B-300 flow cells using 150 bp paired end runs and NovaSeq workflow-series 10B sequencing run confirm genomic DNA quantity and quality by performing DNA concentration measurements and volume checks Re-attempt sequencing in the case that DNA quality and quantity is sufficient, but sample fails sequencing-based quality control Examine agarose gels on all samples as an industry-standard method for screening DNA marker quality prepare PCR-free sequence libraries for all samples Sequence the libraries at a minimum of 30x coverag...

Official solicitation and documents

The full solicitation, any attachments, and the actual submission instructions live on the official listing, not on this page. Oppward summarizes public record data; it does not host or mirror the source documents.

View the official listing on SAM.gov

Oppward is an independent service and is not affiliated with, endorsed by, or sponsored by SAM.gov or any government agency. This page is a plain-English summary of public record data; the linked source above is the authoritative listing.

How to bid on this

This is a contract solicitation, not a grant. To bid, you submit a proposal (usually a price and a description of how you would do the work) directly to the government, through the channel the official listing specifies, not through Oppward.

Make sure your business has an active SAM.gov registration. You cannot be paid on a federal contract without one.
Read the full solicitation on the official listing above, especially the scope of work, not just this summary. Our guide to reading a solicitation walks through what to look for.
Check the set-aside listed above and confirm your business actually qualifies for it before you spend time on a proposal. See our guide to set-asides if the category is unfamiliar.
Submit your proposal by the deadline, using the exact submission method the official listing states. A technically on-time bid sent the wrong way is often treated as late.