Contract · No Set aside used

TECHNOLOGY LICENSING OPPORTUNITY: Platform to Accelerate Discovery of Tailored Industrial Enzymes (PAD-TIE)

Agency: ENERGY, DEPARTMENT OF / ENERGY, DEPARTMENT OF
Location: Los Alamos, NM
Amount: Amount not listed
Deadline: Closes in 75 days (Oct 1, 2026)
Posted: Jul 8, 2026
Set-aside: No Set aside used
NAICS code: 541714

What this contract is for

NREL and Los Alamos National Laboratory’s PAD-TIE platform is an advanced screening system designed to accelerate the discovery and optimization of enzymes that break down polyethylene terephthalate (PET), one of the most widely used plastics. The Challenge: Traditional enzyme development is slow and requires testing individual enzymes under controlled conditions. PAD-TIE overcomes this limitation by simultaneously screening tens of thousands of enzyme variants under industrially relevant conditions for PET degradation. How it Works: Unlike conventional methods, PAD-TIE evaluates enzyme efficiency, stability, and production potential in a single process, ensuring that only the most viable candidates move forward. Validated in lab-scale bioreactors that replicate industrial recycling environments, PAD-TIE supports sustainable PET recycling and upcycling, breaking plastic down into its fundamental building blocks (monomers) for reuse: without the need for harsh chemicals or energy-intensive processes. Key Advantages: Scalable High-Throughput Screening: Evaluates tens of thousands of enzyme variants simultaneously, accelerating discovery. Optimized for Industrial Use: Operates at the optimal temperature for enzymatic PET degradation and high plastic processing efficiency, ensuring compatibility with existing recycling infrastructure. Efficient Resource Use: Uses widely available reagents and eliminates enzyme purification in early screening, reducing material and labor costs. Comprehensive Performance Assessment: Simultaneously measures enzyme activity, stability, and production efficiency, reducing failure rates. Adaptable to Industry Needs: Can be optimized for various processing conditions, different PET compositions, and additives in plastic waste. Market Applications:...

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