Contract · Federal · Total Small Business Set-Aside (FAR 19.5)

NATIONAL CANCER INSTITUTE (NCI) SMALL BUSINESS INNOVATION RESEARCH (SBIR) INNOVATIVE CONCEPT PHASE I AWARD PROGRAM

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
Location: Bethesda, MD
Amount: Amount not listed
Posted: Jul 24, 2026
Set-aside: Total Small Business Set-Aside (FAR 19.5)
NAICS code: 54171 - Scientific Research and Development Services (general category) look up NAICS codes
PSC code: AN12

Timeline

Posted

Jul 24, 2026
Status

Open now

What contracts like this typically pay

No award history yet for this category (NAICS 54171).

What this contract is for

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH
Location: Bethesda, MD
Set-aside: Total Small Business Set-Aside (FAR 19.5)
NAICS: 54171 - Scientific Research and Development Services (general category)
Scope: Federal

THIS EDIT IS TO POST AMENDMENT #2.

AMENDMENT #2 IS TO remove the Data Management Sharing Plan requirement and all references under Sections 5.9 Management and Sharing of Research Data, 6.1 Evaluation Process, Evaluation of Data Management and Sharing Plan, 8.5 Technical Proposal Content (I) Scientific Data Sharing.

The deadline for receipt of proposals remains unchanged at 5:00pm, September 21, 2026.

All other terms and conditions of the solicitation remain unchanged.

PLEASE SEE ATTACHED AMENDMENT #2 PDF.

ORIGINAL SOLICITATION DESCRIPTION: The National Cancer Institute (NCI) invites small business concerns to submit research proposals under this Phase I Small Business Innovation Research (SBIR) contract solicitation.

Firms with the capability to conduct research and development (R&D) in the health-related topic areas referred to below and described more fully in Section 11.0, and to commercialize the results of that R&D, are encouraged to participate.

The topic areas that are being sought under this solicitation are: Topic 1: Development of therapeutic or preventative technologies for treatment or prevention of Pediatric Cancers and/or Rare Cancers.

For this solicitation rare cancers with a 5-year survival rate of less than 50% are encouraged.

Topic 2: Development of devices, diagnostic technologies, or digital health tools for treatment, detection, and diagnosis of Pediatric Cancers and/or Rare Cancers.

For this solicitation, rare cancers with a 5-year survival rate of less than 50% are encouraged.

The National Cancer Institute is soliciting proposals from small business concerns who are looking for an opportunity to perform a few key activities to demonstrate proof-of-concept and feasibility of untested but potentially transformative, game-changing research and development (R&D)...

Official solicitation and documents

The full solicitation, any attachments, and the actual submission instructions live on the official listing, not on this page. Oppward summarizes public record data; it does not host or mirror the source documents.

View the official listing on SAM.gov

Oppward is an independent service and is not affiliated with, endorsed by, or sponsored by SAM.gov or any government agency. This page is a plain-English summary of public record data; the linked source above is the authoritative listing.

How to bid on this

This is a contract solicitation, not a grant. To bid, you submit a proposal (usually a price and a description of how you would do the work) directly to the government, through the channel the official listing specifies, not through Oppward.

Make sure your business has an active SAM.gov registration. You cannot be paid on a federal contract without one.
Read the full solicitation on the official listing above, especially the scope of work, not just this summary. Our guide to reading a solicitation walks through what to look for.
Check the set-aside listed above and confirm your business actually qualifies for it before you spend time on a proposal. See our guide to set-asides if the category is unfamiliar.
Submit your proposal by the deadline, using the exact submission method the official listing states. A technically on-time bid sent the wrong way is often treated as late.